Drug intelligence / Profile preview

[212Pb]Pb-ADVC002

Development stage
Preclinical
Lead developer
Advancell
Modality
Nucleic Acid-Directed Small Molecules → Small Molecules, Antibody-Radionuclide Conjugates → Antibody Conjugates → Antibody-Based Therapeutics, Covalent Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Administration
Parenteral (likely Intravenous Or Injection)
01

Overview

[212Pb]Pb-ADVC002 is a targeted alpha radioligand therapy under preclinical development for the treatment of melanoma. It utilizes the radioisotope lead-212 (²¹²Pb), which emits alpha particles to deliver ionizing radiation directly to tumor cells, causing DNA damage and cell death. The drug is part of a new generation of therapeutic radiopharmaceuticals designed for high specificity and potency against cancer cells, with reduced off-target toxicity compared to traditional therapies. Developed by AdvanCell Isotopes, this agent leverages proprietary isotope production technology to ensure reliable supply and effective delivery in targeted alpha therapy applications[1][2][3][9].

02

Targets

MC1R (Melanocortin Type 1 Receptor)

Beyond the preview

Go deeper on [212Pb]Pb-ADVC002.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Full profile access

Follow clinical development from study design and recruitment through results.

  • Trial phase
  • Status
  • Readouts

Indications & development

Full profile access

Explore development by indication, patient population, and geography.

  • Indications
  • Development status
  • Countries

Licensing & deals

Full profile access

Trace asset ownership, licensing agreements, and commercial partnerships.

  • Partners
  • Deal terms
  • Milestones

Patents & exclusivity

Full profile access

Explore the patent landscape and regulatory exclusivity around an asset.

  • Patents
  • Expiration dates
  • Exclusivity

Competitive landscape

Full profile access

Compare development programs by target, modality, and indication.

  • Competing assets
  • Targets
  • Development stage

Research & analysis

Full profile access

Connect source evidence and development news to your research questions.

  • Publications
  • News
  • Analysis

Bring the full picture into focus.

See how Gosset can support your research on [212Pb]Pb-ADVC002.

Explore the full profile

Gosset Free

Get started with Gosset.

Enter your work email and we’ll be in touch with next steps.

Work email preferred.

Book a call